{"id":1971,"date":"2021-07-26T10:00:53","date_gmt":"2021-07-26T08:00:53","guid":{"rendered":"https:\/\/www.dentalcadmos.com\/a-rare-histological-pattern-of-odontogenic-mandibular-fibromyxoma\/"},"modified":"2021-07-26T10:00:53","modified_gmt":"2021-07-26T08:00:53","slug":"a-rare-histological-pattern-of-odontogenic-mandibular-fibromyxoma","status":"publish","type":"post","link":"https:\/\/www.dentalcadmos.com\/en\/a-rare-histological-pattern-of-odontogenic-mandibular-fibromyxoma\/","title":{"rendered":"A rare histological pattern of odontogenic mandibular fibromyxoma"},"content":{"rendered":"

Objectives  <\/b>Fibromyxoma is a benign locally aggressive odontogenic tumor with a mesenchymal origin, how\u00adever its nature is controversial.<\/p>\n

The World Health Organization both in 2005 classification and 2017 describes it as odontogenic myxoma; at the same time, some authors classify fibromyxoma as a subtype of odontogenic myxoma comprising only a small percent\u00adage of it.<\/p>\n

Due to its rarity, this tu\u00admor is not well known and, espe\u00adcially, it is not well histologically described.<\/p>\n

The only physical ex\u00adamination does not allow per\u00adforming a definitive diagnosis and, frequently, differential diagnoses are carried out in order to shed some light on the nature of neo\u00adplasms.<\/p>\n

Anyway, the surgical re\u00admoval of this lesion is always rec\u00adommended and this condition al\u00adlows carrying out a histological examination. Referral of this case to our attention was surely due to difficulties in differential diagnosis because of complexities in recog\u00adnize, classify and approach this kind of little-known lesion. Histo\u00adlogical analysis plays a key role in diagnosis of this kind of lesions; actually it is likely to have several histological forms of this neo\u00adplasm.<\/p>\n

The aim of this work is to bring to the attention a rare histo\u00adlogical aspect of a surgically treat\u00aded odontogenic mandibular fibro\u00admyxoma, and to describe histo\u00adlogical features in order to provide a more specific typing of lesion. <\/p>\n

Materials and methods<\/b>  A 51 years-old caucasian man was assessed at Section of Oral and Maxillo-facial Surgery of Uni\u00adversity of Verona, three months lat\u00ader of a swelling appearance in the vestibular fornix between lower left canine and premolar. Due to rarity of the disease and lack of clinical knowledge at the moment in this field, patient was referred to our attention after several inconclusive differential diagnoses.<\/p>\n

Physical ex\u00adamination showed a hard swelling in the vestibular fornix between left lower canine and first lower pre\u00admolar for three months. An oral surgical intervention was carried out in order to remove the neo\u00adplasm entirely; therefore a histo\u00adlogical analysis was performed. Physical and computed tomogra\u00adphy examinations allowed assum\u00ading a fibromyxoma, histological analysis confirmed the diagnosis. <\/p>\n

Results<\/b>  Histological analysis defined le\u00adsion as a fibrous-myxoid with dis\u00adcrete cellularity, without significant atypia, including bone chips. Bland stellate fibroblastic cells embedded in a myxoid-fibrous matrix were highlighted, proving the diagnosis of fibromyxoma. <\/p>\n

Conclusions<\/b>  There is reason to state that fibro\u00admyxoma is a very heterogeneous tumor therefore high accuracy in diagnosis is required, by using both instrumental and histological approaches. The clinical observa\u00adtion alone, both pre-surgery and post-surgery, is not a sufficiently reliable indicator to perform a firm diagnosis of this kind of neoplasm.<\/p>\n

The special circumstances of this clinical case seemed to state that confirmed diagnosis and typing are achievable exclusively by his\u00adtological analysis. <\/p>\n

Clinical significance<\/b>  In view of the fact that fibromyxo\u00adma is a rare form of tumor, not yet well histologically described, the clinical case presented strongly suggests to perform, given the need to always remove the lesion, an histological exam\u00adination to better characterize the tumor.<\/p>\n

Following these advices could be make possible to achieve a firm diagnosis and to increase knowledge in classify\u00ading several different forms of fi\u00adbromixoma and, maybe, in ap\u00adproaching them. <\/p>\n

Per continuare la lettura scaricare l’allegato.<\/i><\/p>\n

doi: https:\/\/doi.org\/10.19256\/d.cadmos.01.2020.06<\/a><\/b><\/p>\n","protected":false},"excerpt":{"rendered":"

Objectives  Fibromyxoma is a benign locally aggressive odontogenic tumor with a mesenchymal origin, how\u00adever its nature is controversial. The World Health Organization both in 2005 classification and 2017 describes it as odontogenic myxoma; at the same time, some authors classify fibromyxoma as a subtype of odontogenic myxoma comprising only a small percent\u00adage of it. Due … Continued<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"yoast_head":"\nA rare histological pattern of odontogenic mandibular fibromyxoma - Dental Cadmos<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dentalcadmos.com\/en\/a-rare-histological-pattern-of-odontogenic-mandibular-fibromyxoma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A rare histological pattern of odontogenic mandibular fibromyxoma - Dental Cadmos\" \/>\n<meta property=\"og:description\" content=\"Objectives  Fibromyxoma is a benign locally aggressive odontogenic tumor with a mesenchymal origin, how\u00adever its nature is controversial. 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